Good Simplex Starter Panels?

The 4001 is pretty good. Though I’d like to mention you forgot the 4207, which was similar to the 4208 but had a more modular card-based setup, and was made from 1975 to 1979 (the 4208 came out in either 1969 or 1970.)
The 2001 may have first came out in the late 1970s, but it was more prominent throughout the 1980s (a typical 2001 system may have 2901-9806 horns on 2903 light or strobe plates, 4251 T-bar pulls and older-style Simplex smoke detectors of some kind.) Here are the periods I believe they were out…

4208: 1970-1979
4207: 1975-1979
2001: 1979-1987
4001: 1985-1994
4002: 1986-1996
4004: 1994-2005
4005: 1994-present

If you want to go with addressable devices, or are willing to use Zone Adapter Modules, I would recommend a Simplex 4010. VERY good panel from what I’ve heard. (One of my old schools actually has one, too!)