It really doesn’t matter what devices you put on what zone. The only reason I can think of that you would need to put smoke detectors on a separate zone would be for verification, and even then, you could still have pull stations on a zone with verification, it would just take a long time for the zone to go into alarm. The 4 wire i3 would have 2 wires going to the resettable power and 2 wires going to either zone.
This thread on this forum helped me out a lot, it explains very good tips on how to take care of a panel: <URL url="Basic Rules for Panel Care text=“viewtopic.php?f=60&t=3191”>Basic Rules for Panel Care
Also, I would read the manual, it’s actually not that long of a read and it has some useful information in it: https://www.firelite.com/CatalogDocuments/51512.pdf
Lastly, here’s the manual for the System Sensor i3 series, it has wiring diagrams in it for the 2 and 4 wire versions: System Sensor | Honeywell Building Technologies